John Bluck
NASA Ames Research Center, Moffett Field, CA
Phone: 650/604-5026 or 650/604-9000

Steve Berberich
University of Maryland Biotechnology Institute, Baltimore, MD
(Phone: 410/385-6315)


NASA is providing new insights from space that may help health officials predict outbreaks of deadly water-borne cholera, a
bacterial infection of the small intestine that can be fatal to humans.

Scientists have learned how to use satellites to track blooms of tiny floating plant and animal plankton that carry cholera
bacteria by using satellite data on ocean temperatures, sea height and other climate variables. The work is described in a
recent paper co-authored by University of Maryland Biotechnology Institute (UMBI) and NASA researchers that appeared
in the Proceedings of the National Academy of Sciences.

“These experiments fulfill our hypothesis that cholera is associated with environmental conditions,” said Dr. Rita Colwell,
founder and former president of UMBI, and now Director of the National Science Foundation. She is presently on leave of
absence from the University of Maryland, and is co-author of the cholera-tracking project paper.

The authors found that rising sea temperatures and ocean height near the coast of Bangladesh in the Bay of Bengal from
1992 to 1995 often preceded sudden growth, or “blooms,” of plankton and outbreaks of cholera. Similar application of risk
analysis developed by NASA using satellite data has also been used in the study of diseases such as malaria, Lyme disease
and Rift Valley fever.

“When such a model for Bangladesh is extended to the global scale, it may serve as an early warning system, enabling
effective deployment of resources to minimize or prevent cholera epidemics in cholera-endemic regions,” according to Brad
Lobitz, principal author of the paper and a contract scientist at NASA’s Ames Research Center, located in California’s
Silicon Valley. The scientists correlated years of hospital cholera records from Bangladesh with sea temperature and ocean
height data that came from a variety of satellites and surface observations.

Satellites not only can measure water temperature and ocean height, but also can measure colors that indicate plankton and
chlorophyll over a large sea area, Lobitz explained. Tracking sea temperatures from ships and by other direct measurements
is too expensive to be practical, he added.

Cholera may result in extreme diarrhea, vomiting and loss of water. Victims can die within a day or so unless body fluids are
replenished quickly. The seventh cholera pandemic began in 1961 and now affects six continents, according to the paper. A
pandemic is an epidemic that occurs over a large region.

Sea height is important because tides reach further inland to affect more people who may drink or bathe in brackish water
carrying cholera. “Bangladesh is very low and flat, and tidal effects are felt almost half way up into the country,” said
co-author Louisa Beck of California State University at Monterey Bay and a resident scientist at Ames.

“The 1992-to-1995 study is important because all the remote sensing satellite data are in the public domain,” Beck said. “The
main point is that we obtained the data at no cost because it is available on the web.”

“In most years Bangladesh has two cholera outbreaks,” Lobitz said. “These are in the spring and fall.” The authors discovered
that the sea surface temperatures show an annual cycle similar to the cholera-case data.

The effort was a cooperative project between NASA’s Office of Life and Microgravity Sciences and Applications and
UMBI. The study was also supported by grants from the National Institutes of Health and the Environmental Protection
Agency. The other authors include Byron Wood, Ames; Anwar Huq, UMBI; and George Fuchs and A. S. G. Faruque, the
International Centre for Diarrhoeal Disease Research, Bangladesh. More information about the cholera-tracking project is on
the Internet at:

The researchers used data from three Earth-observing satellites in the study: a National Oceanographic and Atmospheric
Administration weather satellite, the SeaWiFS instrument aboard the SeaStar (OrbView-2) satellite, and the U.S.- French
TOPEX/Poseidon oceanography satellite. Data from SeaWiFS and TOPEX/Poseidon are provided through NASA’s Office
of Earth Sciences, which is dedicated to studying how natural and human-induced changes affect the Earth’s global