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Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,
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Please Note: The next issue of SPACELINE Current Awareness (List #811) will be sent
on Friday, August 17.

Papers deriving from NASA support:

1

Beheshti A, Ray S, Fogle H, Berrios D, Costes SV.

A microRNA signature and TGF-β1 response were identified as the key master regulators for spaceflight response.

PLoS One. 2018 Jul 25;13(7):e0199621.

https://www.ncbi.nlm.nih.gov/pubmed/30044882

Note: ISS results.
GeneLab: “All raw data used in this manuscript is available on
https://genelab.nasa.gov/
.” This article may be obtained online without charge.

Journal Impact Factor: 2.806

Funding:
“Research
funding was provided by the GeneLab Project at NASA Ames Research
Center, through NASA’s Space Biology Program in the Division of Space
Life and Physical Sciences Research
and Applications (SLPSRA).”

 

2

Ramachandran V, Dalal S, Scheuring RA, Jones JA.

Musculoskeletal injuries in astronauts: Review of pre-flight, in-flight, post-flight, and extravehicular activity injuries.

Curr Pathobiol Rep. 2018 July 28. [Article in Press] Review.

https://link.springer.com/article/10.1007/s40139-018-0172-z

Note:
The studies reviewed data from 1959-2018 and include U.S. space
missions during that
period. This article is part of the journal’s Topical Collection on the
“Effects of the Space Environments on Human Pathobiology.”

Journal Impact Factor: Not available for this journal

Funding:
No funding cited. R.A. Scheuring is affiliated with NASA Johnson Space Center.

 

3

Bell D, Durrance S, Kirk D, Gutierrez H, Woodard D, Avendano J, Sargent JL, Leite C, Saldana B, Melles T, Jackson S, Xu S.

Self-assembly of protein fibrils in microgravity.

Gravit Space Res. 2018 Jul;6(1):10-26.

http://gravitationalandspacebiology.org/index.php/journal/article/view/782

Note:
ISS results. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding:
“This
work was supported by Space Florida, NanoRacks, FSGC, and the Florida
Institute of Technology.” D. Woodard is affiliated with NASA Kennedy
Space Center.

 

4

Alula KM, Resau JH, Patel OV.

Chronic
exposure to altered gravity during the pregnancy-to-lactation
transition affects abundance of cytoskeletal proteins in the rat mammary
gland
.

Gravit Space Res. 2018 Jul;6(1):58-72.

http://gravitationalandspacebiology.org/index.php/journal/article/view/806

Note: Centrifugation was used. This article may be obtained online without charge.

Journal Impact Factor:
Not available for this journal

Funding: “A particular debt of gratitude is owed to Dr. Karen Plaut (Purdue University)
and her collaborators for sharing tissue collected through their NASA grant NNA05CP91A.”

 

5

Evans JM, Knapp CF, Goswami N.

Artificial gravity as a countermeasure to the cardiovascular deconditioning of spaceflight: Gender perspectives.

Front Physiol. 2018 Jul 6;9:716.

https://www.ncbi.nlm.nih.gov/pubmed/30034341

Note:
Centrifugation was used. This article may be obtained online without charge.

Journal Impact Factor: 4.031

Funding:
“The research upon which this review is based, was supported by KY NASA
EPSCoR
Grant NNX07AT58A and the National Center for Research Resources, and
the National Center for Advancing Translational Sciences through NIH
Grant UL1TR000117. Facilities support was provided by the Gravitational
Branch of NASA Ames Research Center and the Human
Research Program of NASA Johnson Space Center.”

 

6

Moonga SS, Qin YX.

MC3T3
infiltration and proliferation in bovine trabecular scaffold regulated
by dynamic flow bioreactor and augmented by low-intensity pulsed
ultrasound
.

J Orthop Translat. 2018 Jul;14:16-22.

https://www.ncbi.nlm.nih.gov/pubmed/30035029

PI: Y.X. Qin

Note:
This article may be obtained online without charge.

Journal Impact Factor:
2.078

Funding: “This work is supported by the National Institute of Health (AR52379, AR61821)
and the National Space Biomedical Research Institute through NASA Cooperative Agreement NCC 9-58.”

 

7

Li Z, Jella KK, Jaafar L, Li S, Park S, Story MD, Wang H, Wang Y, Dynan WS.

Exposure
to galactic cosmic radiation compromises DNA repair and increases the
potential for oncogenic chromosomal rearrangement in bronchial
epithelial cells
.

Sci Rep. 2018 Jul 23;8(1):11038.

https://www.ncbi.nlm.nih.gov/pubmed/30038404

PIs: W.S. Dynan; Y. Wang/W.S. Dynan/NSCOR; J.D. Minna/M.D. Story/NSCOR

Note:
This article may be obtained online without charge.

Journal Impact Factor:
4.259

Funding: “The work was supported by US National Aeronautics and Space Administration (NASA)
award NNX15AD63G (to WSD), NASA NSCOR award NNX11AC30G (to Ya Wang) and NASA NSCOR award NNX11AC54G (to John Minna).”

 

8

Allison KC, Goel N.

Timing of eating in adults across the weight spectrum: Metabolic factors and potential circadian mechanisms.

Physiol Behav. 2018 Aug 1;192:158-66.

https://www.ncbi.nlm.nih.gov/pubmed/29486170

PI: N. Goel

Note:
This article may be obtained online without charge.

Journal Impact Factor: 2.341

Funding: “Both authors derived support for the writing of this review from National Institutes
of Health grants NIH R01DK117488 and NIH R21DK100787.” The PI reports funding under NASA NNX14AN49G.

 

9

Hilleary R, Choi WG, Kim SH, Lim SD, Gilroy S.

Sense and sensibility: The use of fluorescent protein-based genetically encoded biosensors in plants.

Curr Opin Plant Biol. 2018 Dec;46:32-8. Review. Epub 2018 Jul 21.

https://www.ncbi.nlm.nih.gov/pubmed/30041101

PI:
S. Gilroy

Journal Impact Factor: 7.357

Funding:
“The work in the authors’ laboratories is supported by grants from the
National
Science Foundation (MCB1329723 and IOS1557899), The National
Aeronautics and Space Administration (NNX17AD52G and NNX14AT25G) and the
Graduate School of the University of Wisconsin-Madison. RH was
supported by NSF GRF and the Graduate School of the University
of Wisconsin-Madison.”

 

10

Anderson MS, Ewert MK, Keener JF.

Life support baseline values and assumptions document.

Houston, TX: NASA Johnson Space Center, 2018 Jan. 233 p. NASA/TP-2015-218570/Rev 1.

https://ntrs.nasa.gov/?N=123&Ntk=All&Ntt=20180001338&Ntx=mode%20matchallpartial 

Note: This article may be obtained online without charge.

Journal Impact Factor: Not applicable to this publication

Funding: No funding cited. The authors are affiliated with NASA Johnson Space Center.

______________________________________________________

 

Other papers of interest:

 

1

Gravely AK, Vlasov A, Freeman A, Wu K, Szewczyk NJ, D’Cruz R, Batt J.

Levels of acid sphingomyelinase (ASM) in
Caenorhabditis elegans in microgravity
.

Gravit Space Res. 2018 Jul;6(1):27-36.

http://gravitationalandspacebiology.org/index.php/journal/article/view/803

Note: ISS results. This article may be obtained online without charge.

 

2

Brcic J, Suedfeld P, Johnson P, Huynh T, Gushin V.

Humor as a coping strategy in spaceflight.

Acta Astronaut. 2018 Jul 26. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0094576518303618

Note: Astronauts and cosmonauts who participated in the study have flown on a variety of
missions.

 

3

Wang L, Han F, Zheng HQ.

Photoperiod-controlling guttation and growth of rice seedlings under microgravity on board Chinese Spacelab TG-2.

Microgravity Sci Technol. 2018 Jul 23. [Article in Press]

https://link.springer.com/article/10.1007%2Fs12217-018-9644-3

Note:
Chinese Spacelab TG-2 results.

 

4

Llanos PJ, Andrijauskaite K, Rubinstein MP, Chan SSL.

Investigation of zebrafish larvae behavior as precursor for suborbital flights: Feasibility study.

Gravit Space Res. 2018 Jul;6(1):37-57.

http://gravitationalandspacebiology.org/index.php/journal/article/view/812

Note: Centrifugation was used. This article may be obtained online without charge.

 

5

Maltsev AV.

Agmatine modulates calcium handling in cardiomyocytes of hibernating ground squirrels through calcium-sensing receptor signaling.

Cell Signal. 2018 Nov;51:1-12. Epub 2018 Jul 17.

https://www.ncbi.nlm.nih.gov/pubmed/30030121

 

6

Vale P.

Impact of light quality and space weather in
Alexandrium catenella (Dinophyceae) cultures
.

Life Sci Space Res. 2018 Jul 31. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552418300269

 

7

Chang H, Lei T, Ma X, Zhang J, Wang H, Zhang X, Gao YF.

Muscle-specific
activation of calpain system in hindlimb unloading rats and hibernating
Daurian ground squirrels: A comparison between artificial and natural
disuse
.

J Comp Physiol B. 2018 Jul 23. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30039299

Note: Hindlimb unloading study.

 

8

Furukawa T, Tanimoto K, Fukazawa T, Imura T, Kawahara Y, Yuge L.

Erratum: Publisher Correction: Simulated microgravity attenuates myogenic differentiation via epigenetic regulations.

npj Microgravity. 2018 Jul 18;4:15.

https://www.ncbi.nlm.nih.gov/pubmed/30038958

Note:
“The original version of this Article contained an error in Fig. 4.
Fig. 4B was partly
cropped, which obscured some of the sequence information.” This has
been corrected in both the PDF and HTML versions of the article. The
original citation appeared in SPACELINE Current Awareness List #800, 25
May 2018,
https://www.ncbi.nlm.nih.gov/pubmed/29845109. Both articles may be obtained online without charge.

 

9

Valenzuela PL, Morales JS, Pareja-Galeano H, Izquierdo M, Emanuele E, de la Villa P, Lucia A.

Physical strategies to prevent disuse-induced functional decline in the elderly.

Ageing Res Rev. 2018 Jul 18;47:80-8.

https://www.ncbi.nlm.nih.gov/pubmed/30031068

 

10

Menezes KM, Wang H, Hada M, Saganti PB.

Radiation matters of the heart: A mini review.

Front Cardiovasc Med. 2018 Jul 9;5:83.

https://www.ncbi.nlm.nih.gov/pubmed/30038908

Note:
This article may be obtained online without charge.

 

11

Hinterecker T, Leroy C, Kirschhock ME, Zhao M, Butz MV, Bulthoff HH, Meilinger T.

Spatial memory for vertical locations.

J Exp Psychol Learn Mem Cogn. 2018 Jul 26. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30047770

 

12

Zitting KM, Munch MY, Cain SW, Wang W, Wong A, Ronda JM, Aeschbach D, Czeisler CA, Duffy JF.

Young adults are more vulnerable to chronic sleep deficiency and recurrent circadian disruption than older adults.

Sci Rep. 2018 Jul 23;8(1):11052.

https://www.ncbi.nlm.nih.gov/pubmed/30038272

Note:
This article may be obtained online without charge.

 

13

Kozeko LY, Buy DD, Pirko YV, Blume YB, Kordyum EL.

Clinorotation affects induction of the heat shock response in
Arabidopsis thaliana seedlings
.

Gravit Space Res. 2018 Jul;6(1):2-9.

http://gravitationalandspacebiology.org/index.php/journal/article/view/791

Note: A clinostat was used. This article may be obtained online without charge.